Wycombe are just four points behind the Black Cats ahead of the match having played the same number of matches.
Following back-to-back wins, Sunderland’s preparations have been disrupted after multiple Covid-19 cases.
As a result, Sunderland have recalled Jack Diamond, Josh Hawkes and Anthony Patterson so they can fulfil the fixture and name a matchday squad.
Wycombe usually play with a back three and wing-backs, meaning Sunderland are likely to match them up.
The Black Cats claimed a 3-1 win when the sides met at the Stadium of Light back in August, courtesy of a Ross Stewart brace and Elliot Embleton strike.
Here’s the Sunderland side which could start this weekend:
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1. GK: Anthony Patterson
The goalkeeper had only played one game after returning to Notts County on loan but has been recalled due to Covid-19 cases in the Sunderland squad. That suggests the 21-year-old will be needed to start the match. Photo: JPI Media
2. RWB: Carl Winchester
Has missed the side's last two games with a minor knock but could return to the side. Photo: JPI Media
3. CB: Bailey Wright
The Aussie has filled in at right-back in recent matches, allowing the side to switch from a back three to a back four. Photo: JPI Media
4. CB: Tom Flanagan
Stood up to the physical test against Sheffield Wednesday and will have to do so again against a strong Wycombe side. Photo: JPI Media